The increase is based on the figures from the last 5 years.
Over 3,300 children under the age of 15 got anti-depressant medication last year.
According to freedom of information files, it's a 55% increase on five years earlier.
495 children under the age of 11 got the drugs in 2021, under three schemes run by the HSE.
Professor of psychiatry in Trinity College Dublin, Brendan Kelly, says it's not the typical treatment.