A local TD says GPs are facing enormous pressure, and can't take on more patients.
Almost 130 people in the midlands are without a GP to take them on as patients.
The highest number of applications in the region is in Offaly, where 81 people had applied between January of last year and last month, according to figures from the HSE.
In Westmeath, 30 people are still searching for GP care and in Laois the figure comes in at 18.
The report was issued to Independent Laois Offaly TD, Carol Nolan, who says GP practices are facing enormous pressure and want to take on more patients but don't have enough time or resources.
She said: "I have been consistently highlighting the major deficits in healthcare service provision in Laois-Offaly and indeed right across the Midlands, but these numbers are truly alarming.
I am dealing with people who have moved home to Offaly or Laois and who assumed that they would eventually find at least one GP practice that could add them and their children on as patients.
Those people are now left entirely stranded in terms of access and prescriptions."
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