The retailer has 3 outlets in the region.
All Argos stores in the Republic of Ireland have ceased trading this evening.
30 stores in total closed their doors at 5pm with 500 employees now unemployed.
That includes three stores in the midlands - Athlone, Tullamore and Portlaoise.
Its parent company, Sainsbury's, says it will still honour un-used Euro gift cards via its UK operations, which remain unaffected by the decision to end trading in the Republic.