The men, one aged in his 30s and the other in his late teens, are currently being detained at Athlone Garda Station.
Two men remain in Garda custody this morning, in connection with a Garda investigation into the fatal assault of a man in Athlone.
The man died following the incident at a taxi-rank in Church Street in the early hours of Saturday morning.
The 49-year-old man was assaulted near a taxi rank in the Church Street area of Athlone, at around 2.30am on Saturday.
He suffered serious injuries and was taken to Portiuncula University Hospital, Ballinasloe, where he was later pronounced dead.
Yesterday, Gardai arrested two men under suspicion of assault.
The men, one aged in his 30s and one in his late teens, are currently being detained at Athlone Garda Station.
Gardaí want to speak anyone who was in the taxi rank waiting area on Church Street between 2.15am and 3am on Saturday morning.
Anyone who may have provided assistance to the injured man is also asked to make contact with Gardaí.
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