He joins Tom O'Toole on the sidelines.
Iain Henderson has been ruled out of the Guinness Six Nations clash with Italy this weekend.
The Ulster lock returned a positive COVID result during the routine testing of squad and management upon arrival into camp on Monday evening.
He joins provincial team-mate Tom O'Toole on the sidelines after the prop picked up an injury during last weekend's win over the Dragons.
No other positive results have been returned in the Irish camp.
The IRFU have released a statement saying that Henderson is 'well and has left Ireland camp to complete his period of isolation at home.'