The first legs will be played on 11th March.
Manchester United will face Italian giants AC Milan in the last-16 of the Europa League.
The tie will see striker Zlatan Ibrahimovic reunited with his former club.
The 39-year-old has been with the Serie A club since December 2019 and previously played with United between 2016 and 2018.
Arsenal meanwhie will take on Greek side Olympiacos and Tottenham will face Dinamo Zagreb of Croatia.
Scottish Premiership leaders Rangers have been drawn to play Slavia Prague - who knocked out Leicester City last night,.
The first legs will be played on 11th March.