After a solid win over Wexford, Kilkenny travel to O'Moore Park for Laois' opening fixture.
Laois get their Leinster Under 20 Hurling Championship campaign underway against Kilkenny this weekend.
The O'Moore County play hosts to Kilkenny, who got their campaign off to a strong start with a win against Wexford in the opening game of the group.
They will be hoping to cause a shock just as their minors did against the same opposition two years ago.
The game at O'Moore Park throws in at 1pm on Saturday.