A number of players stepped away from the set up in January.
There'll be eleven changes to the Offaly Senior Hurling Panel in 2021.
Notable call ups from the U-20's are Shinrone's Eamon Cleary, St Rynagh's Luke O'Connor, Padraig Cantwell of Shamrocks.
It was announced in January that Kilcormac/Killoughey's Cillian Kiely wouldn't be a part of the set up this season for personal reasons.
His younger brother Cathal is also dealing with an injury and is out for the time being.
Other withdrawals earlier this year were Birr's Brendan Murphy, Seir Kieran's Kevin Dunne, Andy Flynn of Lusmagh, James Dempsey and David O'Toole-Greene of Kinnitty and Shamrocks.
Three players from Shinrone have also left the set up, Sean Cleary, Dan Doughan and Michael Cleary.
A total of 36 players have been chosen by Michael Fennelly for the upcoming National League Campaign which starts a week on Saturday against Meath.
The Offaly panel in full is:
Aaron Maher (Ballinamere), Adrian Hynes (Seir Kieran), Aidan Treacy (St Rynagh's), Ben Conneely (St Rynagh's), Brian Duignan (Durrrow), Brian Watkins (Birr), Ciaran Burke (Durrow), Colm Gath (Drumcullen), Conor Clancy (St Rynagh's), Conor Langton (Clodiagh Gaels), Damien Egan (Belmont), David King (Coolderry), David Nally (Ferbane), Dylan Watkins (Birr), Eamon Cleary (Shinrone), Eimhin Kelly (Lusmagh), Eoghan Cahill (Birr), Jason Sampson (Shinrone), Joey Keenaghan (Clodiagh Gaels), John Murphy (Ballinamere), Jordan Quinn (Kilcormac/Killoughey), Killian Sampson (Shinrone), Liam Langton (Clodiagh Gaels), Leon Fox (Belmont), Luke O'Connor (St Rynagh's), Oisin Kelly (Belmont), Paddy Delaney (Kinnitty), Paddy Rigney (Kinnitty), Pauric Cantwell (Shamrocks), Peter Geraghty (Kilcormac/Killoughey), Podge Guinan (Drumcullen), Rory Carty (Birr), Ross Ravenhill (Durrow), Shane Dooley (Tullamore), Shane Kinsella (Kinnitty), Stephen Corcoran (Coolderry).