However the Laois club will be on the road for the President's National Cup.
Portlaoise Panthers have landed home ties in their first round, and prospective second round fixtures for the Paudie O'Connor National Cup.
The Laois club welcome the newly promoted Trinity Meteors to St Mary's Hall for their first round tie on the weekend of the third and fourth of November.
The winner of that game will have home advantage against St Paul's in the quarter-finals.
The other quarter-final ties for the Paudie O'Connor Cup are as follows:
Liffey Celtics host Fr. Matthews, and UCC Glanmire travel to Killester.
While the winner of Gurranabraher Brunell and SETU Waterford Wildcats will play University of Galway Mystics.
Those games will be run off on the weekend of the seventh and eighth of December.
In the Presidents' National Cup,
The Panthers have been drawn to face Moycullen in Galway on the first weekend of November.
With the winners playing away against either Killarney Cougars or Drogheda Wolves in the last eight in December.
Paudie O'Connor National Cup
Round 1 - 3rd/4th November
Midland Park Portlaoise Panthers v Trinity Meteors
Gurranabraher Credit Union Brunell v SETU Waterford Wildcats
Quarter-finals - 7th/8th December
Midland Park Portlaoise Panthers/Trinity Meteors v Utility Trust St. Paul's
Gurranabraher Credit Union Brunell/SETU Waterford Wildcats v University of Galway Maree
FloMAX Liffey Celtics v Catalyst Fr. Mathews
Killester v The Address UCC Glanmire
Presidents' National Cup
Round 1 - 3rd/4th November
Maigh Cuilinn v ND Audit Portlaoise Panthers
Titans v Scotts Lakers Killarney
Limerick Sport Eagles v Ulster University
Killarney Cougars v Drogheda Wolves
Moy Tolka Rovers v SETU Waterford Vikings
Mater Private Malahide v Tipp Talons
Joels Dublin Lions v Limerick Celtics
Carrick Cruisers v Team Northwest
Quarter-finals - 7th/8th December
Killarney Cougars /Drogheda Wolves v Maigh Cuilinn/ND Audit Portlaoise Panthers
Titans/Scotts Lakers Killarney v Limerick Sport Eagles/Ulster University
Moy Tolka Rovers/SETU Waterford Vikings v Mater Private Malahide/Tipp Talons
Joels Dublin Lions/Limerick Celtics v Carrick Cruisers/Team Northwest
Panthers Aiming To Extend Perfect Record
Razor Thin Margins In KK v Castletown Geoghegan - Gerry Buckley
Tullamore Need "Triple Layered Duvet" Blanket Defence For Cuala Contest
Garrycastle Playing For Leinster Final Place
Panthers Hunting For Third Super League Win
Tommy Fitzgerald Announced As New Laois Hurling Manager
Offaly's Izuchukwu In Line For Senior International Debut
Kilcormac Braced For "Top Class" Castletown Geoghegan
"One Of The Greatest Footballers To Play The Game" - Nigel Dunne Pays Tribute To Brian Fenton
Two Midlands Clubs Appear On The Podium In Senior Cross Country Championships
Ireland Have A Lot To Work On Following Narrow Victory - Henshaw
Westmeath And Offaly Fighters Win National Boxing Crowns
Hand "Thrilled" With KK's Leinster Win
St Brigid's Crowned Leinster Champions In Tullamore
Clara's Shane Lowry Bags Third Place Finish At DP World Tour Championship
Castletown Geoghegan Success Down To Years Of Hard Work - Alan Mangan
Westmeath Club Deliver Plans On New Pitches
Gleeson Steps Down As Laois Manager Following Cancer Diagnosis
Women's Super League: Panthers Welcome Killester To St Mary's Hall