Cyrus Christie has been called up to replace him.
Republic of Ireland captain Seamus Coleman will miss the FIFA 2022 World Cup qualifier against Serbia due to injury.
The Ireland skipper suffered an injury during the 1-1 draw against Azerbaijan and will miss the match at the Aviva Stadium on Tuesday, September 7.
Cyrus Christie has been called up and will link up with the squad later tomorrow ahead of MD-1 training at the Aviva Stadium.